Spontaneous post-partum inhibitor to factor VIIi clotting anti- gen--a cause of life-threatening hemorrhage
Lutze, G.; Canzler, E.; Presser, H.J.
Zentralblatt für Gynakologie 111(3): 167-172
1989
ISSN/ISBN: 0044-4197 PMID: 2497601 Document Number: 340322
Pathologic inhibitors of blood coagulation as cause of acquired haemostatic failure are rare. We report about a 23 years old primigravida with a life-threatening haemorrhage post partum. Analysis of coagulation parameters showed the presence of inhibitor to factor VIII. We reacted successfully with cyclophosphamid and cryoprecipitated factor VIII. References to diagnostic and therapy of pathologic clotting factor inhibitors are described.
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