Present and future of insulin treatment
Skrha, J.
Vnitrni Lekarstvi 59(3): 209-213
2013
ISSN/ISBN: 0042-773X PMID: 23713190 Document Number: 665958
The main goal of modern insulin treatment is to bring diabetes control to physiological regulation as close as possible. We move from human insulin to insulin analogues which may due to their properties reduce glucose excursions (glucose variability) with hypoglycemic and hyperglycemic episodes. Besides short acting insulin analogues diminishing extension of hyperinsulinemia and postprandial hypoglycemia observed by human insulin treatment, the long-acting analogues are used to create stabilized insulin level and to prevent nocturnal hypoglycemia. Individualized insulin treatment is the basement for modern trends in diabetology.