[Clinical pharmacology and biological characteristics of 3-tetrahydropyranyl ether of 17-beta-estradiol] Farmacologia clinica e caratteristiche biologiche del 3-tetraidropiraniletere del 17-beta-estradiolo.
Effects of the 3-tetrahydropyranyl ether of 17beta-estradiol on vaginal cytology, endometrium, and blood lipids were studied in 55 women aged 56-87 years. Stimulative effects on vaginal cytology and endometrial tissue of the "weak estrogen" type were observed after 1 1/2 months of treatment (1-5 mg/day). No "withdrawal" hemorrhage was observed after treatment. No significant change in blood lipid levels was noted during treatment. Tolerance was excellent.