Methods for measuring iodine in urine.
This booklet critically reviews the most widely used techniques for measuring urinary iodine in order to provide planners and laboratory workers a single source of assessment techniques. There are detailed instructions on how to execute each method and general comments on their use in iodine deficiency disorder control programs. Chapter 1 reviews iodine deficiency disorders and urinary iodine levels. Chapter 2 covers principles of urinary iodine methods. Chapter 3 provides an overview of available urinary iodine methods, including important features of each method to consider when selecting the best method for any particular situation. Chapter 4 provides the details of 7 methods, including: method source, reference, brief description, features, equipment, reagents, solutions, procedure, calculation of results, notes, and costs. All the methods, except one, have two steps, a digestion or ashing and a colorimetric determination of iodine. Chapter 5 addresses special technical considerations: safety, an iodine-free work place, minimum laboratory needs, urinary collection and storage of urine samples, computers for data handling, and conversion of SI units. The last chapters list the literature references; resources for methods, laboratory supply houses, and other information on iodine deficiency disorder; and the names of board members, members of the executive committee, regional coordinators, and senior advisors of the International Council for Control of Iodine Deficiency Disorders.