Methods for measuring iodine in urine.

Dunn JT; Crutchfield HE; Gutekunst R; Dunn AD; Bourdoux P; Gaitan E; Karmarkar M; Pineda O; Pino S; Suwanik R
[Amsterdam], Netherlands, International Council for Control of Iodine Deficiency Disorders, 1993. 71 p.

This booklet critically reviews the most widely used techniques for measuring urinary iodine in order to provide planners and laboratory workers a single source of assessment techniques. There are detailed instructions on how to execute each method and general comments on their use in iodine deficiency disorder control programs. Chapter 1 reviews iodine deficiency disorders and urinary iodine levels. Chapter 2 covers principles of urinary iodine methods. Chapter 3 provides an overview of available urinary iodine methods, including important features of each method to consider when selecting the best method for any particular situation. Chapter 4 provides the details of 7 methods, including: method source, reference, brief description, features, equipment, reagents, solutions, procedure, calculation of results, notes, and costs. All the methods, except one, have two steps, a digestion or ashing and a colorimetric determination of iodine. Chapter 5 addresses special technical considerations: safety, an iodine-free work place, minimum laboratory needs, urinary collection and storage of urine samples, computers for data handling, and conversion of SI units. The last chapters list the literature references; resources for methods, laboratory supply houses, and other information on iodine deficiency disorder; and the names of board members, members of the executive committee, regional coordinators, and senior advisors of the International Council for Control of Iodine Deficiency Disorders.

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