The Gonococcal Antimicrobial Surveillance Programme (GASP), WHO Western Pacific Region, 1995.
In 1995, the Gonococcal Antimicrobial Surveillance Program of the World Health Organization's Western Pacific Region examined the susceptibility of 5100 gonococcal isolates to a nominated core group of antibiotics. In the 15 contributing countries, the proportion of isolates resistant to the penicillins by one or more mechanisms ranged from 3.4% (Papua New Guinea) to 97.9% (Viet Nam). Quinolone resistance has been steadily increasing in the Western Pacific Region since 1992 in response to increases in the recommended antibiotic dose and was recorded in nine of the 15 centers in 1995. High-level tetracycline resistance was also present in nine centers in 1995. These findings confirm that gonococcal infections in the Western Pacific Region are becoming more difficult to treat and, as a result, more expensive.