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    Hormonal contraception for men [letter]

    Griffin PD; Farley TM

    Lancet. 1996 Mar 23; 347(9004):830-1.

    The authors explain that Bonn's science and medicine report fails to do justice to recent advances in the search for effective, reversible contraceptive methods for men. Bonn refers to two World Health Organization sponsored clinical studies which established the contraceptive efficacy of hormone-induced azoospermia and severe oligozoospermia, and provided indirect information upon the characteristics and potential acceptability of such methods. Contrary to her supposition, there was no empirical evidence that the nine men in the first study who stopped taking testosterone injections before the full year of contraceptive efficacy did so due to increased aggressiveness. The potential for supraphysiological concentrations of testosterone to induce behavior or mood changes is, however, a genuine concern which needs to be addressed appropriately. Behavioral issues and acceptability to both partners are an important aspect of research into hormonal methods of male fertility regulation. The authors note that although currently available options for men are extremely limited, research into contraception for men is sadly underfunded and underresearched.
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