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MINERVA GINECOLOGICA. 1991 Dec; 43(12):609-10.AIDS continues to pose a grave global problem because it is spreading in the general population by increasing heterosexual transmission and vertical transmission from seropositive mothers to fetuses. A minor rate of transmission has been observed from blood transfusion and blood products. On October 31, 1990 WHO data indicated that a total of 298,914 AIDS cases had been reported. In Africa there were 75,642 cases: 15,569 were in Uganda, 11,732 in Zaire, 9139 in Kenya, 7160 in Malawi, 3647 in the Ivory Coast, 3494 in Zambia, and 3134 in Zimbabwe, with the rest averaging less than 4% of the total African caseload. There were 180,663 cases in the Americas: 149,498 in the US, 11,070 in Brazil, 4941 in Mexico, 4427 in Canada, 2456 in Haiti, 1368 in the Dominican Republic, 870 in Venezuela, 743 in Honduras, 710 in Argentina, 648 in Trinidad an Tobago, 643 in Colombia, 507 in the Bahamas, and 203 in Panama, the rest being less than 200. Asia had only 790 cases: 290 in Japan, 116 in Israel, 48 in India, 45 in Thailand, 37 each in Turkey and the Philippines, 31 in Lebanon, and 27 in Hong Kong. Europe had 39,526 cases: 9718 in France and 6701 in Italy as of June 30, 1990, however, by December 31, 1990 there were 8227 cases reported of whom 4074 had died. There were 6210 in Spain, 5266 in the German Federal Republic, 3798 in England, 1462 in Switzerland, 1443 in the Netherlands, 999 in Romania, 764 in Belgium, 663 in Denmark, 481 in Portugal, 450 in Austria, 443 in Sweden, and 347 in Greece. Little attention has paid to notification in eastern Europe: 40 cases in the USSR, 43 in Poland, 23 in Czechoslovakia, 22 in the German Democratic Republic, 42 in Hungary which is contrasted to 999 cases in Romania. Oceania had 2293 cases: 2040 in Australia, 207 in New Zealand, 16 in French Polynesia, 14 in New Caledonia, 13 in New Guinea, 2 in Tonga, 1 in Fiji, and 1 in the Federated States of Micronesia.
ANTIBIOTICS AND CHEMOTHERAPY. 1991; 43:1-13.Delphi techniques used by the World Health Organization predict more than 6 million cases of AIDS and millions more to be infected with HIV by the year 2000. In the absence of quick solutions to the epidemic, one must prepare to work against and survive it. The modes of HIV transmission are constant and seen widely throughout the world. Transmission may occur through sexual intercourse and the receipt of donated semen; transfusion or surgically-related exposure to blood, blood products, or donated organs; and perinatally from an infected mother to child. There are, however, 3 patterns of transmission. Pattern I transmission is characterized by most cases occurring among homosexual or bisexual males and urban IV-drug users. Pattern II transmission is predominantly through heterosexual intercourse, while pattern III of only few reported cases is observed where HIV was introduced in the early to mid-1980s. Both homosexual and heterosexual transmission have been documented in the latter populations. Significant case underreporting exists in some countries. Investigators are therefore working to find incidence rates of both infection and AIDS cases to better estimate actual present and future needs in the fight against the epidemic. Surveillance data does reveal a rapidly rising and marked number of reported AIDS cases. The cumulative number reported to the World Health Organization increased over 15-fold over the past 4 years to reach 141,894 cases by March 1, 1989. Large, increasing numbers of cases are reported from North and Latin America, Oceania, Western Europe, and areas of central, eastern and southern Africa. 70% of all reported cases were from 42 countries in the Americas. 85% of these are within the United States. Increases in the proportion of IV-drug users who are infected with HIV are noteworthy especially in Western Europe and the U.S. The epidemic in Italy is also specifically discussed.