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    Guidelines for using HIV testing technologies in surveillance: selection, evaluation, and implementation.

    UNAIDS / WHO Working Group on Global HIV / AIDS / STI Surveillance; United States. Centers for Disease Control and Prevention [CDC]

    Geneva, Switzerland, World Health Organization [WHO], 2001. iv, 38 p. (WHO/CDS/CSR/EDC/2001.16; UNAIDS/01.22E)

    As the HIV/AIDS epidemic imposes an ever-larger burden globally, surveillance for HIV becomes more critical in order to understand the trends of the epidemic and to make sound decisions on how best to respond to it. This is especially true in developing countries, which account for a disproportionate share of new and long-standing infections. To help countries focus their surveillance activities in the context of their epidemic state (low-level, concentrated, or generalized), the World Health Organization (WHO) and the Joint United Nations Programme on HIV/ AIDS (UNAIDS) have developed a conceptual framework to improve HIV surveillance—second generation HIV surveillance. Guidelines for second generation HIV surveillance suggest approaches to make better use of data to increase and improve the response to the HIV epidemic. As biological surveillance (serosurveillance) is an important component of most HIV surveillance activities, an understanding of current HIV testing technologies is important. In the context of second generation HIV surveillance, these laboratory guidelines suggest methods for selecting, evaluating, and implementing HIV testing technologies and strategies based on a country’s laboratory infrastructure and surveillance needs. The guidelines provide recommendations for specimen selection, collection, storage, and testing and for the selection and evaluation of appropriate HIV testing strategies and technologies to meet surveillance objectives. Quality assurance issues are also addressed. These technical guidelines are written for HIV surveillance coordinators and other health professionals involved in HIV testing for surveillance purposes in developing countries. They are part of a series of operational guidelines for second generation HIV surveillance systems. (excerpt)
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