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  1. 1
    049146

    WHO Consultation on HIV and Routine Childhood Immunization, Geneva, 12-13 August 1987.

    World Health Organization [WHO]. Special Programme on AIDS

    [Unpublished] 1987. 9 p. (WHO/SPA/GLO/87.3)

    A consultation in August 1987, co-sponsored by the World Health Organization (WHO) Special Program on Acquired Immunodeficiency Syndrome (AIDS) and the Expanded Program on Immunization (EPI), was called to review available information on human immunodeficiency virus (HIV) infection and immunization guidelines. Of particular concern was the safety and efficacy of the 6 EPI vaccines in children with HIV infection. Concerns have been raised that children infected with HIV who receive routine childhood immunizations may have decreased immune responses and be at greater risk of adverse effects or acceleration of HIV-induced immunosuppression. Available data, although limited, suggest that there is no risk of accelerating HIV infection by the simultaneous administration of multiple antigens, except perhaps in the case of Bacille Calmette-Guerin (BCG) immunization. In areas where exposure to measles and poliomyelitis is high, the benefits of immunization far outweigh the risks of adverse effects from immunization, even in the presence of symptomatic HIV infection. Overall, consultation participants affirmed the validity of the following EPI guidelines developed in 1986: 1) in countries where HIV infection is problematic, children should be immunized with EPI antigens according to the standard schedule, including children with asymptomatic HIV infection; and 2) unimmunized individuals with clinical AIDS in countries where the EPI target diseases remain serious risks should not receive BCG, but should be given the remaining 5 vaccines. Since vaccine-related adverse effects are minimized and vaccine responses optimized by beginning immunization before the progression of HIV-induced immunosuppression, children should be immunized as early in life as possible.
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  2. 2
    046823

    The state of the world's children 1988.

    Grant JP

    Oxford, England, Oxford University Press, 1988. [9], 86 p.

    The 1988 UNICEF report on the world's children contains chapters describing the multi-sectorial alliance to support child health, the current emphasis on ORT and immunization, the effect of recession on vulnerable children, family rights to knowledge of basic health facts, and support for women in the developing world. Each chapter is illustrated by graphs. There are side panels on programs in specific countries, including Senegal, Syria, Colombia, Bangladesh, Turkey, India, Honduras, Japan and Southern Africa, and highlighted programs including immunization, AIDS, ORT, breast-feeding and tobacco as a test of health. The SAARC is a new regional organization of southern Asian countries committed to immunization and other health goals. Tables of health statistics of the world's nations, divided into 4 groups by "Under 5 Mortality Rate" present basic indicators, nutrition/malnutrition data, health information, education, literacy and media data, demographic indicators, economic indicators and data pertaining to women. The absolute numbers of child deaths had fallen to 16 million in 1980, from 25 million in 1950. Saving children's lives will not exacerbate the population problem because, realizing that their children will survive, families will have fewer children. Furthermore, the methods used to reduce mortality, such as breast feeding and empowerment of families to control their lives, are known to reduce fertility.
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