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WHO recommendations for prevention and treatment of maternal peripartum infections: Highlights and key messages from the World Health Organization's 2015 global recommendations.
[Geneva, Switzerland], WHO, 2015 Sep.  p. (WHO/RHR/15.19; WHO/MCA/15.01)Bacterial infections around the time of childbirth account for about one-tenth of maternal deaths and contribute to severe morbidity and long-term disability for many affected women. Standard infection prevention and control measures are a cornerstone of peripartum infection prevention (e.g., hand hygiene and use of clean equipment). WHO recommendations for prevention and treatment of maternal peripartum infections include both recommended and non-recommended interventions during labour, childbirth, and the postpartum period. Clinical monitoring, early detection, and prompt treatment of peripartum infection with an appropriate antibiotic regimen are essential for reducing death and morbidity in affected women. Recommendations for antibiotic prophylaxis / treatment for specific indications balance health benefits for the mother and newborn with safety concerns (e.g., adverse effects) and the public health imperative to control antibiotic resistance.
Geneva, Switzerland, WHO, 2014.  p.Optimizing outcomes for women in labour at the global level requires evidence-based guidance of health workers to improve care through appropriate patient selection and use of effective interventions. In this regard, WHO published recommendations for induction of labour in 2011. The goal of the present guideline is to consolidate the guidance for effective interventions that are needed to reduce the global burden of prolonged labour and its consequences. The primary target audience includes health professionals responsible for developing national and local health protocols and policies, as well as obstetricians, midwives, nurses, general medical practitioners, managers of maternal and child health programmes, and public health policy-makers in all settings. Augmentation of labour is the process of stimulating the uterus to increase the frequency, duration and intensity of contractions after the onset of spontaneous labour. It has commonly been used to treat delayed labour when poor uterine contractions are assessed to be the underlying cause. The WHO technical consultation adopted 20 recommendations covering practices relating to the diagnosis, prevention and treatment of delayed progress in the first stage of labour, and supportive care for women undergoing labour augmentation. For each recommendation, the quality of the supporting evidence was graded as very low, low, moderate or high. The contributing experts qualified the strength of these recommendations (as strong or weak) by considering the quality of the evidence and other factors, including values and preferences of stakeholders, the magnitude of effect, the balance of benefits versus harms, resource use and the feasibility of each recommendation. To ensure that each recommendation is correctly understood and used in practice, additional remarks and an evidence summary have also been prepared, and these are provided in the full document, below each recommendation. Guideline users should refer to this information in the full version of the guideline if they are in any doubt as to the basis for any of the recommendations. (Excerpts)