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    Antibiotic treatment of community acquired pneumonia in well-nourished young Nigerian children [letter]

    Ajayl MT; Oladokun RA; Falade AG

    Journal of Tropical Pediatrics. 2005 Oct; 51(5):319-320.

    Worldwide, Streptococcus pneumoniae and Haemophilus influenzae are reported to be responsible for about 57 per cent of community-acquired pneumonia in children, whereas, Staphylococcus aureus contributes only 14 per cent. Based on this, the WHO has recommended the use of crystalline penicillin and amoxycillin given sequentially for the treatment of severe community-acquired pneumonia. However, this appears not to have been fully accepted in Nigeria, presumably because most aetiological studies of pneumonia in the country have indicated that S. aureus and Klebsiella spp. predominate. However, those in whom S. aureus and Klebsiella spp were isolated were not all cases of community-acquired pneumonia; while a substantial number were malnourished. Therefore, we carried out a retrospective study of the use of the sequentially administered intravenous (i.v.) crystalline penicillin and oral amoxycillin, or i.v. flucloxacillin given simultaneously with intramuscular (i.m.) gentamicin, in the treatment of severe community-acquired pneumonia in well-nourished under-five-year olds in a hospital setting. (excerpt)
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