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    306957

    Determinants of aflatoxin M1 in breast milk in a selected group of Egyptian mothers.

    Polychronaki N; Turner PC; Mykkanen H; Gong Y; Amra H

    Food Additives and Contaminants. 2006 Jul; 23(7):700-708.

    In Egypt, there is a paucity of biomarker data on aflatoxin (AF) exposure. The study assessed the level and frequency of breast milk, AFM/1 as a biomarker of maternal exposure. Breast milk samples were collected from a selected groups of 388 Egyptian lactating mothers of children attending the New El-Qalyub Hospital, Qalyubiyah governorate, Egypt, during May-September 2003. Following aflatoxin extraction, AFM/1 levels were assessed by high-performance liquid chromatography (HPLC) with fluorescence detection. Approximately 36% of mothers tested positive for AFM/1 ( median 13.5 pg ml, interquartile range (IQR) 10.27-21.43) Non-working status (p=0.018, odds ration (OR) =2.87), obesity (p=0.004, OR=3.0), high corn oil consumption (p = 0.028 OR =3.57), contributed to the occurrence of AF in breast milk. AFM/1 contamination of breast milk was frequent, albeit at moderate levels. Growth and development of the infant is rapid and thus it is possible that AF exposure through breast milk has a significant health effect. (author's)
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