Granulomas

Donovanosis in developed countries: neglected or misdiagnosed disease? [letter]

Author: 
Morrone A; Toma L; Franco G; Latini O
Source: 
International Journal of STD and AIDS. 2003 Apr; 14(4):288-289.
Abstract: 

There is a possibility that in the developed world some cases of granuloma inguinale in human mobile populations are not identified by clinicians inexperienced in tropical diseases, or that they are treated and accidentally cured through aspecific use of antibiotics, which are more and more often self-administered. As a matter of fact the Calymmatobacterium granulomatis is responsive to a number of commonly used antibiotics. (excerpt)

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Malignant transformation of donovanosis. A case report.

Author: 
Thappa DM; Senthikumar M; Laxmisha C
Source: 
Indian Journal of Sexually Transmitted Diseases. 2004; 25(2):77-78.
Abstract: 

A 25-year old male truck driver married for last two years presented to us with single, painless, reddish ulcerated lesion over the penis of four years duration. On examination, a single, non-tender, fleshy, exuberant, beefy red granulation tissue involving most of the glans penis (including urethral meatus) was seen. Tissue smear from the edge of the genital sore stained with slow Giemsa stain showed "Donovan bodies" located within large vacuolated monocyte.

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Ocular toxocariasis in a north Indian population.

Author: 
Mirdha BR; Khokar SK
Source: 
Journal of Tropical Pediatrics. 2002 Dec; 48(6):328-330.
Abstract: 

Sera form 68 patients aged 1–30 years, suffering from posterior pole granuloma, peripheral granuloma, uveitis, endophthalmitis, optic neuritis and with a clinical diagnosis of suspected ocular toxocariasis, were tested for the presence of anti-Toxocara antibodies. Antibodies to Toxocara were detected in 11 (17 per cent) subjects less than 15 years old and three (4 per cent) subjects more than 15 years of age using enzyme-linked immunosorbent assay. None of the controls sera (other helminthic diseases) were positive for anti-Toxocara antibody. (author’s)

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Prevalence of pregnancy related oral granuloma in a Nigerian population group and the possible role ...

Author: 
Lawoyin JO; Lawoyin DO; Arowojolu MO; Lawoyin T; Akande OO
Source: 
African Journal of Medicine and Medical Sciences. 2003 Dec; 32(4):409-412.
Abstract: 

A clinicopathological survey on pregnancy related tumours was carried out on 400 randomly selected pregnant Nigerian women. Fifteen (15) cases of pregnancy granuloma or 'epulis gravidanum' were found. Of these subjects, 287 representing 71.8 percent were on birth control before conception, while 113 or 28.2 percent were not. Nine(9) cases of pregnancy tumour were found in the group on birth control pills and six (6) in the group not on birth control representing an incidence of 3.1 and 5.3 percent respectively.

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ER, PR and Ki-67 expression status in granulomatous and chronic non-specific endometritis.

Author: 
Mishra K; Wadhwa N; Guleria K; Agarwal S
Source: 
Journal of Obstetrics and Gynaecology Research. 2008 Jun; 34(3):371-378.
Abstract: 

Aim: To study the changes in the histological pattern, distribution and intensity of sex steroid receptors (estrogen and progesterone) and cell proliferation by Ki-67 expression by semi-quantitative scores in granulomatous and chronic non-specific endometritis in the premenstrual phase. Methods: A retrospective study was conducted on 20 cases of granulomatous endometritis, 10 of chronic non-specific endometritis and 30 age matched (+or- 2 years) controls with no endometrial lesions.

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Review of seizures and status epilepticus in HIV and tuberculosis with preliminary view of Bombay ho ...

Author: 
Bharucha NE; Raven RH; Nambiar VK
Source: 
Epilepsia. 2009 Dec; 50 Suppl 12:64-6.
Abstract: 

This article discusses status epilepticus (SE), human immunodeficiency virus (HIV), and tuberculosis in the developing world and specifically looks at an experience in a Bombay hospital involving these three ailments.

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[Sarcoidosis and pregnancy: one case]

Author: 
Hamdani Z; Yousfi MM; Hassirahou D; El Amrani S; Ouazzani MC
Source: 
Espérance Médicale. 2001 Jul; 8(74):359-361.
Abstract: 

This article is based on pregnancy and sarcoidosis, or Besnier-Boeck-Schaumann disease (BBS), a multisystemic granulomatosis secondary to an immune response whose origin is still unknown, and involves a particular case. This case involves a 36-year-old woman, with no notable pathological history, 18 weeks pregnant and presenting several papular and modular lesions located on the face, neck, back of the hands of the elbows. Monitoring detected no sign of activity of the disease, nor of fetal abnormalities; the patient delivered a healthy newborn vaginally.

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Study of tuberculous lymphadenitis spectrum of cytomorphologic changes and acid fast bacilli positiv ...

Author: 
Akhter S; Baba KM; Nabi A
Source: 
JK-PRACTITIONER. 2001 Jan-Mar; 8(1):23-6.
Abstract: 

The study presents a detailed analysis of fine needle aspiration smears from 215 clinically diagnosed patients of tuberculous lymphadenitis with a correlation between gross appearance of the aspirate, cytomorphologic features and acid-fast bacilli (AFB) positivity. The aspirate was of three types: 1) mixed with blood, 2) purulent, and 3) cheesy. The main cytomorphologic feature was presence of epithelioid cell granulomas with or without Langhan's giant cells.

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The need to reassess the value of fine needle aspiration in the diagnosis of tuberculous cervical l ...

Author: 
Hasibi M; Rezaii J; Kermani ZM; Asadollahi M; Rashidi A
Source: 
Scandinavian Journal of Infectious Diseases. 2007; 39:750-751.
Abstract: 

Iran is an endemic country for tuberculosis (TB). After the eradication and efficient control of some 'priority' infectious diseases such as polio and measles, TB has now turned into a major public health problem in Iran. Cervical lymphadenitis is the most common form of extrapulmonary TB, accounting for 30-40% of TB cases and fine needle aspiration (FNA) is widely accepted as the first diagnostic modality of choice in this entity, especially in countries where mycobacterial infection is endemic.

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Application of polymerase chain reaction technique for laboratory diagnosis of cutaneous tuberculosi ...

Author: 
Khosravi AD; Omidian M
Source: 
Pakistan Journal of Medical Sciences. 2006 Jul-Sep; 22(3):291-294.
Abstract: 

The objective was the evaluation of the role of polymerase chain reaction (PCR) for the detection of Mycobacterium tuberculosis (MTB) DNA as a diagnostic aid in cutaneous tuberculosis. Study Design: Descriptive study. Duration and place of study: TB reference laboratory, PHLS, Ahvaz, Iran from May 2001 to December 2001. Thirty formalin-fixed, paraffin-embedded samples belonging to 28 patients were analyzed. Tissue sections were treated by lysis buffer containing proteinase K and DNA was extracted by using standard extraction kit.

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