Title: HIV-1 infection and fertility in Dar es Salaam, Tanzania.

POPLINE Document Number: 319205

Author(s):

Sedgh G
Larsen U
Spiegelman D
Msamanga G
Fawzi WW

Source citation:

African Journal of Reproductive Health, 2006;10(3):41-52.

Abstract:

The objective of this study was to examine the association of HIV-1 infection with rates of pregnancy and pregnancy loss in Dar es Salaam, Tanzania. A retrospective cohort study of 1,006 HIV-infected women and 485 uninfected women was employed. In multivariate analyses controlling for other predictors of pregnancy, the association of HIV-seropositivity with a woman's reported number of pregnancies was of borderline significance (RR = 1.13, 95% CI =1 .00, 1.27). HIV infection was not associated with pregnancy loss in multivariate analysis. The adjusted pregnancy rate ratio comparing HIV-positive women at the earliest stages of infection to all uninfected women was 1.22 (95% CI = 1.04, 1.42). HIV infection was not associated with female fertility when comparing women in the most advanced stages of infection to all uninfected women. We conclude that HIV-1 infected women had higher pregnancy rates than uninfected women. This association disappeared when analyses were limited to women with advanced disease. Abstract word count: 150. (author's)

Keywords:

Tanzania
Research Report
Retrospective Studies
HIV Positive Persons
Women
Fertility
Pregnancy History
Reproductive Behavior
Cohort Analysis
Multivariate Analysis
Pregnancy Outcomes
Pregnancy Rate
Developing Countries
Africa, Eastern
Africa, Sub Saharan
Africa
Studies
Research Methodology
Persons Living With HIV/AIDS
HIV Infections
Viral Diseases
Diseases
Demographic Factors
Population
Population Dynamics
Fertility Measurements
Data Analysis
Pregnancy
Reproduction