Title: Rotavirus vaccines -- An update.

POPLINE Document Number: 313338

Author(s):

Dennehy PH

Source citation:

Vaccine, 2007 Apr 20;25(16):3137-3141.

Abstract:

Rotavirus infection is the most common cause of severe diarrhea disease in infants and young children worldwide and continues to have a major global impact on childhood morbidity and mortality. Vaccination is the only control measure likely to have a significant impact on the incidence of severe dehydrating rotavirus disease. Rotavirus disease prevention efforts suffered a severe setback in 1999 with the withdrawal of the RRV-TV vaccine less than a year after its introduction. Several new rotavirus vaccines have been developed and have proven to be safe and efficacious. These new safe and effective rotavirus vaccines offer the best hope of reducing the toll of acute rotavirus gastroenteritis in both developed and developing countries. (author's)

Keywords:

United States
Research Report
Child
Infant
Rotavirus
Viral Diseases
Infections
Diarrhea
Child Mortality
Morbidity
Gastrointestinal Effects
Vaccines
Prevention and Control
North America
Americas
Developed Countries
Youth
Age Factors
Population Characteristics
Demographic Factors
Population
Diseases
Mortality
Population Dynamics
Physiology
Biology
Medical Procedures
Medicine
Health Services
Delivery of Health Care
Health