Title: Evaluation of lipid profile in adolescents during long-term use of combined oral hormonal contraceptives.

POPLINE Document Number: 281343

Author(s):

Guazzelli CA
Lindsey PC
de Araújo FF
Barbieri M
Petta CA

Source citation:

Contraception, 2005;71:118-121.

Abstract:

The study evaluated the effects of the long-term use of a combined oral hormonal contraceptive containing 30 µg ethinyl estradiol and 75 µg gestodene in adolescents. Thirty-three volunteers, aged from 14 to 19 years, who used the oral contraceptive for three consecutive years, were studied. Evaluation of total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides was made before use and after 1, 2 and 3 years. During the 3-year study period, total cholesterol, HDL-C, LDL-C and triglyceride levels were significantly higher than previous measurements, but average values did not exceed the normal range. Compared to the first year, the second- and third-year cholesterol, HDL-C, LDL-C and triglyceride levels were not significantly different. (author's)

Spanish Abstract:

El estudio evaluó los efectos del uso a largo plazo de anticonceptivos hormonales orales combinados con contenido de 30 µg de etinil-estradiol y 75 µg de gestodeno. Se estudiaron treinta y tres voluntarias de 14 a 19 años que emplearon el anticonceptivo oral durante tres años consecutivos. Previo a la administración, al año, a los dos y a los tres años se evaluaron colesterol total, colesterol de lipoproteínas de alta densidad (HDL-C, high-density lipoprotein cholesterol), colesterol de lipoproteínas de baja densidad (LDL-C, low-density lipoprotein cholesterol) y triglicéridos. Durante el período del estudio de 3 años, los niveles de colesterol total, colesterol de lipoproteínas de alta densidad, colesterol de lipoproteínas de baja densidad y triglicéridos fueron significativamente superiores a las mediciones previas, pero los valores promedio no superaron el rango normal. Los niveles de colesterol total, HDL-C, LDL-C y triglicéridos para el segundo y tercer años no difirieron significativamente de los valores registrados en el primer año. (del autor)

Keywords:

Brazil
Research Report
Evaluation
Adolescents, Female
Oral Contraceptives, Combined
Ethinyl Estradiol
Gestodene
Longterm Effects
Cholesterol
Lipids
Risk Factors
Health
Developing Countries
South America, Eastern
South America
Latin America
Americas
Adolescents
Youth
Age Factors
Population Characteristics
Demographic Factors
Population
Oral Contraceptives
Contraceptive Methods
Contraception
Family Planning
Contraceptive Agents, Estrogen
Contraceptive Agents, Female
Contraceptive Agents
Contraceptive Agents, Progestin
Time Factors
Population Dynamics
Physiology
Biology

Population Reports information:

Topic: oral contraceptives