Title: New antibiotic for TB?

POPLINE Document Number: 277009

Source citation:

JAMA. Journal of the American Medical Association, 2005 Jan 19;293(3):286.

Abstract:

A new antibiotic shows promise for treating tuberculosis (TB) more swiftly than current anti-TB drugs, according to research by scientists in Belgium, France, Sweden, and the United States. The study was published on December 9 in an online edition of Science (http://www.sciencemag.org). The drug, called R207910, belongs to a newly discovered family of compounds called diarylquinolines and appears to have a mechanism of action that differs from that of other antibiotics used to treat TB or other infections, impeding the cell's ability to produce energy in the form of adenosine triphosphate. Cell culture studies found that R207910 potently inhibits both drug-sensitive and drug-resistant TB bacteria, the researchers reported. (excerpt)

Keywords:

United States
Europe, Western
Recommendations
Evaluation
Target Population
Tuberculosis
Antibiotics
Administration and Dosage
Time Factors
Cytologic Effects
Developed Countries
North America
Americas
Europe
Program Design
Programs
Organization and Administration
Infections
Diseases
Drugs
Treatment
Population Dynamics
Demographic Factors
Population
Physiology
Biology