Title: Need to confirm HTLV-1 screening assays [letter].

POPLINE Document Number: 270902

Author(s):

Hrdy DB
Carlson JR
Yee JL
Armstrong MY

Source citation:

Lancet, 1989 Jan 14;1(8629):109.

Abstract:

Babona, Nurse, and Kazura reported a prevalence of positive results to a screen of sera from New Guinea for HTLV-1. The screen was an agglutination assay. Hndy, Carlson, and Yee tested sera in New Guinea and the Solomon Islands for HTLV-1 by ELISA, and found a similar prevalence of positive results. When testing the same sera by western blot (WB), only a small percentage of the Elisa positives were WB positives. This result may be due to problems with the HTLV-1 WB assay, cross reactivity with other immune complexes or malaria, or an HTLV-1 variant.

Keywords:

AIDS
Viral Diseases
HIV Infections
Laboratory Procedures
Solomon Islands
Papua New Guinea
Oceania
Examinations and Diagnoses
Laboratory Examinations and Diagnoses
Incidence
Critique
Diseases
Developing Countries
Measurement
Research Methodology