POPLINE Document Number: 049092
Author(s):
Liukko P
Erkkola R
Gronroos M
Lammintausta R
Source citation:
ANNALES CHIRURGIAE ET GYNAECOLOGIAE. SUPPLEMENTUM, 1987;76 Suppl 202:50-3.
Abstract:
Body weight, systolic and diastolic blood pressure, and plasma renin activity were longitudinally followed in 2 groups of oral contraceptive (OC) acceptors: 10 women who received a combination OC containing 0.150 mg levonorgestrel and 0.030 mg ethinyl estradiol and 10 women who received an OC that combined 0.150 mg desogestrel and 0.030 mg ethinyl estradiol. The study participants were monitored over a 2-year period. Most studies of use of OCs containing 0.050 mg or over of ethinyl estradiol have recorded a gradual rise in blood pressure during the 1st 2 years of use, after which systolic pressure stabilizes while diastolic continues to rise slightly. On the other hand, some studies have found that blood pressure increases are less notable when the OC contains only 0.030 mg estrogen. In this study, all 3 parameters -- body weight, systolic and diastolic blood pressure, and plasma renin activity--remained unchanged throughout the entire study period. In addition, there were no significant differences in results between the 2 different types of combined OCs. It is concluded that both the preparations tested are likely to be safer than OCs containing higher doses of estrogen and progestin.
Keywords:
Prospective StudiesIndex page
Oral Contraceptives, Combined
Oral Contraceptives, Side Effects
Contraceptive Agents, Female
Contraception
Family Planning
Ethinyl Estradiol
Hormones
Reproductive Control Agents
Levonorgestrel
Body Weight
Blood Pressure
Physiology
Estrogens
Side Effects
Contraceptive Agents, Side Effects
Studies
Research Methodology
Oral Contraceptives
Contraceptive Methods
Contraceptive Safety
Safety
Public Health
Health
Contraceptive Agents
Contraceptive Agents, Estrogen
Endocrine System
Biology
Contraceptive Agents, Progestin
Hemic System
Treatment