Title: Effect of graded doses of ionizing radiation on the human testis.

POPLINE Document Number: 018247

Author(s):

Rowley MJ
Leach DR
Warner GA
Heller CG

Source citation:

Radiation Research, 1974 Sep;59(3):665-78.

Abstract:

A portable unit was developed to provide uniform irradiation of the human testes. The device had built-in radiological protection and provided a dosage independent of the subject geometry, uniform to within +or- 5%. Single doses, between 8-600 rad were administered to the testes of human subjects. Observations were made both before and following irradiation. Parameters evaluated included sperm concentration, motility and morphology, seminal fluid volume, plasma and urinary gonadotropin and testosterone levels, urinary estrogens, and comparison of testicular biopsies taken before and after irradiation in the same subject. Dose-response relationships and recovery times were determined for each dose range studied. (author's modified)

Keywords:

Human Volunteers
Testis
Histology
Sperm Count
Complications
Age Factors
Luteinizing Hormone
Follicle Stimulating Hormone
Testosterone
Estrogens
Clinical Research
Research Methodology
Genitalia, Male
Genitalia
Urogenital System
Physiology
Biology
Laboratory Procedures
Laboratory Examinations and Diagnoses
Examinations and Diagnoses
Diseases
Population Characteristics
Demographic Factors
Population
Gonadotropins, Pituitary
Gonadotropins
Hormones
Endocrine System
Androgens