Title: Problems posed by potential gonococcal vaccines viewed from the vantage point of a control agency.

POPLINE Document Number: 018233

Author(s):

Robbins JB

Source citation:

British Journal of Venereal Diseases, 1977 Jun;53(3):170-2.

Abstract:

Progress in the characterization of Neisseria gonorrhoeae and other bacterial pathogens has suggested that immunoprophylaxis for gonorrhea may be possible despite the well-known propensity for reinfection. Pili, outer membrane proteins, a capsular polysaccharide, and the lipopolysaccharide may be important gonococcal virulence factors, and immune components (probably antibodies) to more than 1 of these antigens may be required to confer immunity. A study of antigenic polymorphism of these structures should identify disease isolates more precisely and provide information about the relationship between variants of these gonococcal structure and gonococcal virulence. (author's)

Keywords:

Sexually Transmitted Diseases
Vaccination
Immunization
Research Methodology
Reproductive Tract Infections
Infections
Diseases
Primary Health Care
Health Services
Delivery of Health Care
Health