Title: The treatment of missed abortion by high dosage Syntocinon intravenous infusion.

POPLINE Document Number: 620207

Author(s):

Liggins GC

Source citation:

JOURNAL OF OBSTETRICS AND GYNAECOLOGY OF THE BRITISH COMMONWEALTH, 1962 Apr;69(2):277-81.

Abstract:

The attempt was made to determine the reliability of high dosage Syntocinon infusions in the treatment of missed abortions and to determine undesirable side effects. 30 women who were admitted during the 1959-1961 period to the National Women's Hospital in Auckland, New Zealand with a diagnosis of missed abortion were treated with high dosage Syntocinon drip. Treatment was successful in 27 cases and unsuccessful in 3 cases, 1 of these being a normal pregnancy wrongly diagnosed as missed abortion. Severe water intoxication was induced in 1 patient. Subsequently, Syntocinon was shown to be anti-diuretic in all cases investigated. Neither adverse cardiovascular reactions or impaired blood clotting powers were noted. This form of treatment appears to be highly effective in missed abortions where the uterus exceeds the size of a 10-week pregnancy. With simple precautions taken to prevent excessive water retention, it is a safe procedure.

Keywords:

Evaluation
New Zealand
Abortion
Developed Countries
Oceania
Fertility Control, Postconception
Family Planning