Title: Deladroxate for the prevention of ovulation.

POPLINE Document Number: 640164

Author(s):

Rutherford RN
Banks AL
Coburn WA

Source citation:

Fertility and Sterility, 1964;15(6):648-652.

Abstract:

The article presents a study assessing the effects of a monthly injection of dihydroxyprogesterone acetophenide (Deladroxate) combined with either 10, 20, or 30 mg of estradiol ethanate in 3 groups of 10 women. Ovulation was entirely inhibited during the interval between shots. A high degree of side effects was observed, e.g., breast tenderness, heavy or prolonged menstrual flow, premenstrual fluid retention, and decreased libido. These side effects have been minimized by using dosages with less estrogen and more progestogen without depriving the drug of its antiovulatory effect.(JPS JPS)

Keywords:

Algestone Acetophenide
Ethinyl Estradiol
Ovulation Suppression
Method Acceptability
Reversibility
Administration and Dosage
Side Effects
Injectables
Contraceptive Agents, Side Effects
Women
Contraceptive Agents, Progestin
Contraceptive Agents, Female
Contraceptive Agents
Contraception
Family Planning
Contraceptive Agents, Estrogen
Contraceptive Mode of Action
Contraceptive Usage
Drugs
Treatment
Contraceptive Methods
Demographic Factors
Population